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7483 Pathology

An 8-month-old male infant is admitted to the hospital because of a bacterial respiratory infection. The infant responds to appropriate antibiotic therapy, but is readmitted several weeks later because of severe otitis media. Over the next several months, the infant is admitted to the hospital multiple times for recurrent bacterial infections. Workup reveals extremely low serum antibody levels. The infant has no previous history of viral or fungal infections. The most likely diagnosis for this infant is

AIsolated IgA deficiency
BX-linked agammaglobulinemia of Bruton
CChronic granulomatous disease
DDiGeorge's syndrome
Pathology
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