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7081 Pathology

A 58-year-old woman undergoes routine colonoscopy. A 2-cm submucosal nodule is identified in the appendix. Biopsy of the nodule shows nests of cells with round, uniform nuclei. Electron microscopy reveals numerous neuroendocrine granules in the cytoplasm. This patient’s neoplastic disease is associated with which of the following clinical features?

ACongestive hea failure
BFlushing and wheezing
CMuscular dystrophy
DProgressive systemic sclerosis
Pathology
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