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6691 Pathology

A 60-year-old woman with a history of diabetes mellitus has had left-sided chest pain radiating to the arm for the past 5 hours. Serial measurements of serum creatine kinase-MB levels show an elevated level 24 hours after the onset of pain. Partial thromboplastin time (PTT) and prothrombin time (PT) are normal. Coronary angiography shows occlusion of the left anterior descending artery. Which of the following mechanisms is the most likely cause of thrombosis in this patient?

AAntibody inhibitor to coagulation
BDamage to endothelium
CDecreased antithrombin III level
DDecreased tissue plasminogen activator
Pathology
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