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6530 Pathology

A 28-year-old, previously healthy man has noted increasing fatigue for the past 6 months and the formation of bruises after minimal trauma. Over the past 2 days, he has developed a cough. On physical examination, his temperature is 38.9deg C, and he has diffuse rales in both lungs. He has no hepatosplenomegaly and no lymphadenopathy. Laboratory findings include a sputum culture positive for Streptococcus pneumoniae, hemoglobin of 7.2 g/dL, hematocrit of 21.7%, platelet count of 23,400/ mm3, WBC count of 1310/ mm3, prothrombin time of 13 seconds, partial thromboplastin time of 28 seconds, and total bilirubin of 1 mg/dL. The ANA test result is negative. What is the most likely explanation of these findings?

AHematopoietic stem cell defect
BHemolysis of antibody-coated cells
CIncreased susceptibility to lysis by complement
DMetastatic adenocarcinoma to bone marrow
Pathology
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6531 Pathology

A 24-year-old woman with a history of heavy and painful menstrual periods has been having difficulty conceiving despite months of trying to become pregnant. Fuher workup includes a bimanual pelvic examination and an ultrasound, which demonstrates a mass in the uterus that is presumed to be a leiomyoma. This mass is a

Abenign tumor of mesenchymal tissue
Bbenign tumor of surface epithelium
Cmalignant tumor of epithelial tissue
Dmalignant tumor of mesenchymal tissue.
Pathology
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