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6317 Pathology

A 22-year-old woman from a large Italian family is screened for a familial blood disorder. The results of laboratory studies include a hemoglobin of 9.5 g/dL and a smear displaying mild microcytosis, hypochromia, and a few target cells. Haemoglobin electrophoresis shows a mild increase in haemoglobin A2 (7.5%). What is the appropriate diagnosis?

AAnemia of chronic disease
BG6PD deficiency
CHeterozygous b-thalassemia
DHomozygous b-thalassemia
Pathology
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