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5792 Pathology

Regarding oncogenesis, all are true except:

AProto-oncogenes are activated by chromosomal translocation
BMalignant transformations involves accumulation of mutations in proto-oncogenes and tumor suppressor genes
CPoint mutation of somatic cells
DIncrease in telomerase activity causes anti-tumor effects
Pathology
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5794 Pathology

An epidemiologic study of a community shows an increased incidence of basal cell and squamous cell carcinomas in adults. These lesions are distributed predominantly on palms and soles. Analysis of groundwater pumped from wells for drinking shows increased levels of heavy metal used in pressure-treated lumber (with a greenish hue), insecticides, and herbicides. Which of the following metals is most likely implicated by this study?

AArsenic
BBeryllium
CCadmium
DLead
Pathology
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