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541 Pathology

17-year-old boy presented with complain of petechiae. O/E ,sternal tenderness is present. BM biopsy show hypercellularity and more than 20% Lymphoblast. Peripheral smear show ||| TLC and presence of lymphoblast . On X ray. retrosternal mass is seen. All are true about condition patient is suffering except?

AIt has good prognosis
BNotch gene mutation present
CAn immature T-cell phenotype (Tdt/CD34/CD7 positive)
DThymic involvement is seen
Pathology
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542 Pathology

A 9-year-old girl develops widespread pinpoint skin hemorrhages. She recovered from a fl u-like illness 1 week earlier. Laboratory findings reveal a platelet count of 20,000/mL but no other abnormalities. Her bone marrow shows an increased number of megakaryocytes. The platelet count is normal after 2 months. Which of the following is the appropriate diagnosis?

AAntiphospholipid antibody syndrome
BDisseminated intravascular coagulation
CHemolytic-uremic syndrome
DIdiopathic thrombocytopenic purpura
Pathology
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549 Pathology

A patient undergoing chest x-ray following an automobile accident is found to have an enlarged mediastinum with bilateral hilar and right paratracheal adenopathy. The patient has been asymptomatic, but careful examination demonstrates an enlarged cervical lymph node. This node is biopsied and demonstrates involvement by small, non-caseating granulomas. Occasional giant cells with stellate inclusions are seen within the granulomas. These are most likely which of the following?

AAnitschkow cells
BAschoff bodies
CAsteroid bodies
DPaget's cells
Pathology
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