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4930 Pathology

True about cystic fibrosis

AThe underlying defect in sodium channel function
BThe immune reactive trypsin (I) may be checked on the Guthrie card (Correct Answer)
CIn most cases the gene c defect is a loss of Valine at position 508 on chromosome 7
DA sweat test with a sodium content above 40 mmol/l is diagnos c