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461 Pathology

A 24-year-old male presented with a 4-year history of abdominal pain, periodic diarrhea, low-grade fever, and easy fatigability is found to have an entero-enteric fistula on contrast radiography. Colonoscopy shows “cobblestone” mucosa that has linear ulcerations with “skip areas” of normal bowel wall. Which of the following is most likely explanation of fistula formation in this patient?

AIntramural granulomas
BTransmural inflammation
CMarked lymphoid reaction
DSkip lesions of the intestinal wall
Pathology
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466 Pathology

A 50-year-old lady presented with a 3-month history of pain in the lower third of the right thigh. There was no local swelling; tenderness was present on deep pressure. Plain X-rays showed an ill-defined intra medullary lesion with blotchy calcification at the lower end of the right femoral diaphysis, possibly enchondroma or chondrosarcoma. Sections showed a cailaginous tumor. Which of the following histological features (if seen) would be most helpful to differentiate the two tumours?

AFocal necrosis and lobulation
BTumor permeation between bone trabecuae at periphery
CExtensive myxoid change
DHigh cellularity
Pathology
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