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3544 Pathology

A 60-year-old man is referred because of splenomegaly and generalized lymphadenopathy. The total white blood cell count is markedly elevated, and the differential count reveals a preponderance of mature appearing lymphocytes. Bone marrow examination reveals a diffuse infiltration with similar-appearing lymphocytes. Which of the following statements best characterizes this disorder?

AA progressive increase in the number of myeloblasts and promyelocytes is indicative of acceleration of the disease process.
BBacterial infections are common early in the disease due to hypogammaglobulinemia
CMean survival is less than 1 year after diagnosis
DMyelofibrosis is a common complication
Pathology
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