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3380 Pathology

A 50-year-old man dies of a respiratory illness that had been characterized by dyspnea, cough, and wheezing expiration of many years’ duration. Initially episodic, his “attacks” had increased in frequency and at the time of death had become continuous and intractable. At autopsy, which of the following is the most likely histologic finding in the lungs?

ABronchial smooth muscle hyperophy with proliferation of eosinophils (Correct Answer)
BDiffuse alveolar damage with leakage of protein-rich fluid into alveolar spaces
CDilation of air spaces with destruction of alveolar walls
DHypoplasia of bronchial mucus-secreting submucosal glands