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3286 Pathology

A 68 year old woman was admitted with a history of weakness for two months. On examination, cervical lymph nodes were found enlarged and spleen was palpable 2 cm below the costal margin. Her hemoglobin was 10.5 g/dl, platelet count 27 x 109/L and total leukocyte count 40 x 109/L, which included 80 % mature lymphoid cells with coarse clumped chromatin. Bone marrow revealed a nodular lymphoid infiltrate. The peripheral blood lymphoid cells were positive for CD19, CD5, CD20 and CD23 and were negative for CD79B and FMC-7. The histopathological examination of the lymph node in this patient will most likely exhibit effacement of lymph node architecture by?

AA monomorphic lymphoid proliferation with admixed proliferation centers
BA polymorphous population of lymphocytes, plasma cells, eosinophils and scattered large binucleated cells
CA predominantly follicular pattern with variably-sized follicles effacing nodal architecture
DA diffuse proliferation of medium to large lymphoid cells with high mitotic rate.
Pathology
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3288 Pathology

A 5-year-old boy has a history of recurrent urinary tract infections. Urine cultures have grown Escherichia coli, Proteus mirabilis, and Enterococcus. Physical examination now shows an abnormal constricted opening of the urethra on the ventral aspect of the penis, 1.5 cm from the tip of the glans penis. There also is a cryptorchid testis on the right and an inguinal hernia on the left. What term best describes the child’s penile abnormality?

ABalanitis
BBowen disease
CEpispadias
DHypospadias
Pathology
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3290 Pathology

Anaphylaxis refers to the

ASevere reaction following injection of protein solutions in a sensitized individual
BSevere reaction following primary injection of protein solutions
CState of immunity developed by repeated injections of any foreign substance
DAll of the above
Pathology
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