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2597 Pathology

A 66-year-old woman dies of severe congestive hea failure. Her past medical history is remarkable for rheumatoid ahritis that first manifested at the age of 35. The autopsy revealed splenomegaly, hepatomegaly, and glomerulopathy. The spleen, liver, and kidneys showed a similar waxy texture. Which of the following mechanisms explains these clinical and pathologic findings?

AAccumulation of amyloid
BAtherosclerosis of coronary aeries
CCoxsackievirus myocarditis
DMutation of myosin chain genes
Pathology
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