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1829 Pathology

A 40-year-old woman with a history of rheumatic fever presents with shoness of breath, weight loss, fatigue and abdominal distension. Physical examination shows rales in the lungs, hepatosplenomegaly and 2+ pitting edema of the legs. A chest X-ray reveals only left atrial enlargement and pulmonary edema. What is the most likely cause of pulmonary edema in this patient?

AAoic insufficiency
BAoic stenosis
CMitral stenosis
DTricuspid insufficiency
Pathology
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1836 Pathology

A 15 year old male presents with hematuria. he has previous diagnoses of deafness and corneal dystrophy. Urinalysis shows I + proteins, no ketones, no glucose, 1+blood, and no leukocytes. A renal biopsy reveals tubular epithelial foam cells by light microscopy. By electron microscopy the glomerular basement membrane shows areas of attenuation, with splitting and lamination of lamina dense in other thickened areas. The most probable diagnosis is ?

AAcute tubular necrosis
BBerger disease
CMembranous glomerulonephritis
DA 1po syndrome
Pathology
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