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14806 Pathology

A 50-year-old woman presents with lower back pain of 3 weeks in duration. Radiologic studies reveal several discrete lytic lesions in the lumbar back and pelvis. Laboratory studies show elevated serum levels of alkaline phosphatase. Serum calcium, serum protein, and peripheral blood smears are normal. Aspiration biopsy of a pelvic lesion shows keratin-positive cells. Which of the following is the most likely diagnosis?

AChondrosarcoma
BMetastatic carcinoma
COsteochondroma
DOsteosarcoma
Pathology
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14808 Pathology

A 64-year-old man, who is a chronic alcoholic, presents with fever, chills and increasing shoness of breath. The patient appears in acute respiratory distress and complains of pleuritic chest pain. Physical examination shows crackles and decreased breath sounds over both lung fields. The patient exhibits tachypnea, with flaring of the nares. The sputum is thick, mucoidy and blood-tinged. Which of the following pathogens is the most common cause of this patient’s pulmonary infection?

ALegionella pneumophila
BKlebsiella pneumoniae
CMycoplasma pneumoniae
DStreptococcus pneumoniae
Pathology
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