All Subjects Medicine Surgery Pathology Anatomy Pharmacology Social & Preventive Medicine Microbiology Gynaecology & Obstetrics Dental Physiology Biochemistry Pediatrics
Showing 15321 questions
Sort:
14375 Pathology

A 35-year-old woman with end-stage renal disease of unknown etiology is transplanted with a cadaver kidney. The patient develops oliguia shortly after transplantation and a renal biopsy shows immediate (hyperacute) rejection. Immunosuppression improves renal function. Which of the following represents the principle target for immune attack directed against this patient’s allograft?

AABO antigens
BBacterial antigens
CGlomerular basement membrane antigens
Db2-Microglobulin
Pathology
View Explanation →
14378 Pathology

A 14-year-old girl presents with a 5-day history of hypertension, oliguria, and hematuria. She was seen 2 weeks earlier for a severe throat infection with group A (b-hemolytic) streptococci. A kidney biopsy displays glomerulonephritis. Immunofluorescence staining for which of the following proteins would provide the strongest evidence that this patient’s glomerulonephritis is mediated by immune complexes?

AComplement
BFibrinogen
CHageman factor (clotting factor XII)
DPlasminogen
Pathology
View Explanation →