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13843 Pathology

A 60-year-old woman with type 2 diabetes and end-stage renal disease receives a kidney transplant. Three weeks later, the patient presents with azotemia and oliguria. If this patient has developed acute renal failure, which of the following pathologic findings would be expected on renal biopsy?

AAerial intimal thickening and vascular stenosis
BGlomerulosclerosis
CInterstitial infiltrates of lymphocytes and macrophages
DNeutrophilic vasculitis and fibrinoid necrosis
Pathology
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13844 Pathology

A 2-year-old boy is brought to the physician by his parents, who complain that their son continually loses his balance. They also report that his speech seems more slurred. Physical examination confirms the truncal ataxia and wide-based gait. The child appears lethargic, and there is bobbing of the head while he is sitting. Muscle tone is normal. A lumbar puncture is performed in the patient, and neoplastic cells are found. A suboccipital craniotomy is performed, and a tumor is resected. Microscopic examination of the surgical specimen would most likely reveal which of the following histologic patterns?

AMalignant epithelial cells with prominent tonofilaments
BPerivascular collections of neoplastic lymphocytes
CSmall, hyperchromatic cells and rare neuroblastic rosettes
DVacuolated tumor cells and an abundant capillary network
Pathology
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