Mcq Subject: Pathology

Mediastinal lymph node calcification is seen in which one of the following-

A. Metastatic neoplasm

B. Lymphoma

C. Sarcoidosis

D. Bronchiectasis

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Most aggressive lung CA:

A. Squamous cell CA

B. Adenocarcinoma

C. Small cell lung CA

D. Large cell CA

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Generalised thickening of cortical and cancellous bones is seen in

A. Osteopetrosis

B. Pagets disease

C. Osteogenesis imperfecta

D. Infantile hyperostosis

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Test used for factor VIII deficiency identification is-

A. PT

B. APTT

C. D dimer

D. FDP

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Earliest lesion seen in atherosclerosis is:

A. Fatty streaks

B. Intimal thickening

C. Fibrinoid necrosis

D. Plaque

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A 45-year-old woman complains of severe headaches and difficulty in swallowing. Over the past 6 months, she has noticed small, red lesions around her mouth as well as thickening of her skin. The patient has “stone facies” on physical examination. Which of the following antigens is the most common and most specific target of autoantibody in patients with this disease?

A. C-ANCA (anti-proteinase-3)

B. Double-stranded DNA

C. P-ANCA (anti-myeloperoxidase)

D. Scl-70 (anti-topoisomerase I)

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A 28 year old female teacher is found to have a prolonged bleeding time and normal platelet count. She had a bleeding of “easy bleeding” with frequent bleeding of the gums, epistaxis, cutaneous bleeding and menorrhagia, further testing revealed a deficiency of Von willebrand factor. Which of the following thrombogenic processes involving platelets is most directly impaired?

A. Adhesion

B. Aggregation

C. Formation of fibrinogen bridges

D. Conformational change with activation of phospholipid surface

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Hamartomatous lung tissue is?

A. Hypoplasia of lung

B. Congenital cyst

C. Lobar sequestration

D. Congenital cystic adenomatoid malformation

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Atherosclerosis initiation by fibroblast plaque is mediated by injury to ?

A. Smooth muscle

B. Media

C. Adventitia

D. Endothelium

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Splenomegaly may be a feature of: March 2013

A. Megaloblastic anemia

B. Sickle cell anemia

C. Thalassemia

D. G6PD deficiency

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