Mcq Subject: Pathology

True about Caspases is?

A. Involved in apoptosis

B. Cause necrosis

C. Involved in pain pathway

D. Are cytokines inhibitor

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The Triat in which the parents are clinically normal and only siblings are affected but males and females are affected in equal propoions is:

A. AD

B. AR

C. XLD

D. XLR

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Chemotherapeutic drugs can cause?

A. Only necrosis

B. Only apoptosis

C. Both necrosis and apoptosis

D. Anoikis

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A 40-year-old man presents with a 2-week history of recur- rent oral ulcers, genital ulcers, intermittent arthritic pain of the knees, and abdominal pain. Physical examination reveals shallow ulcerations of the mucosa of the glans penis, as well as oral aphthous ulcers and conjunctivitis. Which of the following is the most likely diagnosis?

A. Behyet disease

B. Genital herpes

C. Gonorrhea

D. Polyarteritis nodosa

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A 49-year-old female taking ibuprofen for increasing joint pain in her hands presents with increasing pain in her midsternal area. Gastroscopy reveals multiple, scattered, punctate hemorrhagic areas in her gastric mucosa. Biopsies from one of these hemorrhagic lesions reveal mucosal erosions with edema and hemorrhage. No mucosal ulceration is seen.

A. Active chronic gastritis

B. Acute gastritis

C. Autoimmune gastritis

D. Chronic gastritis

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Factor V Leiden is caused due to a mutation that results in a substitution at position 506 glutamine to which of the following:

A. Alanine

B. Arginine

C. Glycine

D. Glutamine

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Hereditary spherocytosis is characterized by: March 2004

A. Anemia

B. Splenomegaly

C. Jaundice

D. All of the above

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Autosomal recessive polycystic kidney disease features include:

A. Can be diagnosed intrauterine

B. Proceeds to renal failure till children reaches school going age

C. Can be palpated abdominally

D. Hypertension doesn't develop until late stages of the disease

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Gene involved in Cowden syndrome is

A. P53

B. PTEN

C. RB

D. Ras

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Magic syndrome is seen in:

A. Behcet disease

B. Aphthous major

C. Herpetiform

D. Bloom syndrome

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