Mcq Subject: Pathology

A patient presents with Ahritis, hyperpigmentation of skin and hypogonadism, likely diagnosis is.

A. Hemochromatosis

B. Ectopic ACTH secreting tumour of the lung

C. Wilson's disease

D. Rheumatoid ahritis

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True about Burkitt’s lymphoma are:

A. Associated with t(14:8)

B. Express BCL-2

C. Starry sky pattern on histology

D. Slow progressing

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A patient presented with neck swelling. Cytology showed showed parafollicular cells along with clusters of plasmacytoid and few spindle shaped cells. What investigation should be done to follow up the patient?

A. Calcitonin

B. TSH level

C. Anti TPO antibody

D. TRH

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Annexin V is associated with which of the following?

A. Necrosis

B. Apoptosis

C. Atherosclerosis

D. Inflammation

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Chediak-Higashi syndrome is characterized by

A. Defects in phagolysosome function

B. Defects in macrophage production

C. Defects in leukocyte adhesion

D. Defects in microbicidal activity

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Weight range of adrenal glands in most of cases of cushing’s disease is –

A. 4-11gm

B. 11-13 gm

C. 14-24 gm

D. 25-40 gm

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Obstruction to the flow of CSF at the aqueduct of Sylvius will most likely lead to enlargement of –

A. All of the ventricles

B. Only lateral ventricle

C. Only fourth ventricle

D. Both lateral and third ventricles

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Radiation induced thyroid cancer is –

A. Papillary

B. Follicular

C. Anaplastic

D. Medullary

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Pain of musculoskeletal origin is all except

A. MPDS

B. TMJ arthritis

C. Pos traumatic pain

D. Stylohyoid eagle’s syndrome

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An 18-year-old man moves from sea level to an elevation of 2,400 m to train as a skier. The increased requirement for oxygen delivery to tissues at the higher elevation stimulates the synthesis of a renal hormone (erythropoietin), which targets hematopoietic stem cells in the bone marrow. Erythropoietin promotes the survival of early erythroid progenitor cells primarily through which of the following mechanisms?

A. Altered cell-matrix adhesion

B. Downregulation of p53

C. Enhanced glucose uptake

D. Inhibition of apoptosis

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