Mcq Subject: Pathology
Anticipation is seen in?
A. Translocation
B. Chromosome breaking
C. Trinucleotide - repeat expansion
D. Mitochondrial mutation
View DescriptionMost characteristic of megaloblastic anemia ?
A. Target cell
B. Macrocyte
C. Microovalocyte
D. Macroovalocyte
View DescriptionAll of the following statements are true regarding retinoblastoma, except:
A. Rb genes play major role in cell cycle regulation
B. Require deletion of both the Rb genes
C. Familial variant is autosomal dominant in inheritance
D. Rb gene is on chromosome 14p13
View DescriptionAn 8-year-old child is evaluated by the pediatrician, who notes small cafe-au-lait spots on the child’s torso. In addition, on close inspection of the eyes, the presence of Lisch nodules is noted. The patient is eventually diagnosed with neurofibromatosis type 1. The protein that is mutated in this disorder normally does which of the following functions?
A. Activates the GTPase activity of Ras
B. Cleaves cellular proteins during apoptosis
C. Functions as a cell cycle checkpoint regulator
D. Promotes angiogenesis
View DescriptionA 63-year-old man becomes febrile and begins expectorating large amounts of mucopurulent sputum. Sputum cultures are positive for Gram-positive diplococci. Which of the following mediators of inflammation provides potent chemotactic factors for the directed migration of inflammatory cells into the alveolar air spaces of this patient?
A. Bradykinin
B. Histamine
C. Myeloperoxidase
D. N-formylated peptides
View DescriptionMelanin pigmentation in pregnancy is known as
A. Melasma
B. Melanoma
C. Epulis
D. Melanosis
View DescriptionA 50 years old male with type 2 diabetes mellitus is found to have 24-hour urinary albumin of 250 mg. Which of the following drugs may be used to retard progression of the renal disease?
A. Hydrochlorothiazide
B. Enalapril
C. Amiloride
D. Aspirin
View DescriptionHypercalcemia is seen in which cancer
A. RCC
B. Carcinoma stomach
C. Small cell carcinoma lung
D. Hepatocellular carcinoma
View DescriptionA liver biopsy reveals following findings. What is true about this condition
A. Nodular regenerative hyperplasia of liver induced due to OCP
B. Nutmeg liver with dark areas of perivenular dead hepatocytes and gray areas of periportal viable hepatocytes
C. Nutmeg liver with pale areas of necrosis and dark congested areas of perivenular viable hepatocytes
D. Cirrhotic liver with fibrotic nodules.
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