Mcq Subject: Pathology

Neuroleptic malignant syndrome is characterized by

A. Bradycardia

B. Labile hypeension

C. Hypotonia

D. Hypothermia

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RBC cast in the microscopic examination of the urine is an indicator of

A. Acute glomerulonephritis

B. Acute pyelonephritis

C. Chronic glomerulonephritis

D. Nephrotic syndrome

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Neo-adjuvant chemotherapy used esophageal carcinoma

A. Doxorubicin

B. Cisplatin

C. 5-Fu-Leucovarin

D. Mitomycin C

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On routine examination, it is discovered that a 35-year-old woman had been exposed in-utero to Diethylstilbestrol (DES) administered to her mother, who had had a history of recurrent spontaneous aboion. This history suggests that the patient might be at increased risk of which of the following?

A. Adenomyosis

B. Clear cell adenocarcinoma

C. Lichen sclerosus

D. Squamous cell carcinoma

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Intra-epithelial split is seen in :

A. Epidermolysis bullosa.

B. Bullous pemphigoid.

C. Pemphigus vulgaris.

D. All of the above.

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Which of the following is/are an example(s) of non-Mendelian inheritance?

A. Genomic imprinting

B. Uniparental disomy

C. Mitochondrial inheritance

D. All of the above

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Defective chromosome associated with De-George syndrome is –

A. 7

B. 15

C. 17

D. 22

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Spherocytosis of RBC is a common feature in –

A. G6PD deficiency

B. Sickle cell anemia

C. CML

D. All

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Antitumor activity is shown by all except –

A. Cytotoxic T lymphocytes

B. Natural killer cells

C. Basophils

D. Macrophages

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A 30-year-old man has had cramping abdominal pain and bloody diarrhea for the past 4 days. On physical examination, there is diffuse tenderness on palpation of the abdomen. Bowel sounds are present. There are no masses and no organomegaly. A stool culture is positive for Shigella flexneri. The episode resolves spontaneously within 1 week after onset. Six weeks later, he has increasingly severe lower back pain. Physical examination now shows stiffness of the lumbar spine and tenderness of the sacroiliac joints. He is treated with nonsteroidal anti-inflammatory agents. Two months later, the back pain recurs, and he complains of redness of the right eye and blurred vision. Serologic testing for which of the following is most likely to be positive in this patient?

A. Borrelia burgdorferi

B. Chlamydia trachomatis

C. Epstein-Barr virus

D. HLA-B27

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