Mcq Subject: Pathology

A 25-year-old woman sustains a deep, open laceration over her right forearm in a motorcycle accident. The wound is cleaned and sutured. Which of the following cell types mediates contraction of the wound to facilitate healing?

A. Endothelial cells

B. Fibroblasts

C. Macrophages

D. Myofibroblasts

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Antibody against tumor cells –

A. MHC-I

B. MHC-II

C. Anti viral

D. Differentiated antigen

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ER-positive status in Ca Breast indicates –

A. Prognosis

B. Etiology

C. Site

D. None

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A 38-year-old woman shows evidence of early cataracts, hair loss, atrophy of skin, osteoporosis, and accelerated atherosclerosis. This patient has most likely inherited mutations in both alleles of a gene that encodes which of the following types of intracellular proteins?

A. Deaminase

B. Helicase

C. Oxidase

D. Polymerase

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Type of necrosis in pancreatitis ?

A. Fibrinoid

B. Coagulative

C. Fat

D. Caseous

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Acute non-suppurative sialdenitis is seen in:

A. Acute bacterial sialadenitis

B. Mumps

C. Chronic bacterial sialadenitis

D. Necrotizing sialometaplasia

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Which of the following is a useful marker to detect autophagy in cells?

A. BAK

B. BAX

C. LC3

D. BID

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AML with worst prognosis –

A. 8/12 translocation

B. Inversion 16

C. Normal cytogenetics

D. Monosomy 7

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A 40 year old woman is on treatment for CLL. Over the past few months she noticed swellings in the neck and axilla which was rapidly increasing in size. She complains of feeling feverish and experiences weight loss. Which of the following is responsible?

A. Richter transformation

B. Progression of CLL

C. Development of secondary infections

D. Immunodeficiency associated hemolytic anemia

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MIC-2 is a marker of-

A. Ewing's sarcoma

B. Osteosarcoma

C. Dermatofibrous protruberans

D. Alveolar cell sarcoma

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