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12987 Pathology

Which one of the following statements about Hemoglobin S (HbS) is not true –

AHemoglobin HbS differs from hemoglobin HbA by the substitution of Val for Glu in position 6 of the beta chain
BOne altered peptide of HbS migrates faster towards the cathode (-) than the corresponding peptide of HbA
CBinding of HbS to the deoxygenated HbA can extend the polymer and cause sickling of the red blood cells
DLowering the concentration of deoxygenated HbS can prevent sickling
Pathology
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