Mcq Subject: Pathology

Question 1

A 60-year-old farmer presents with multiple patches of discoloration on his face. Biopsy of lesional skin reveals actinic keratosis. Which of the following terms best describes this response of the skin to chronic sunlight exposure?

A. Atrophy

B. Dysplasia

C. Hyperplasia

D. Hypertrophy

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Answer

A. Atrophy

B. Dysplasia

C. Hyperplasia

D. Hypertrophy

Question 2

DIC is seen with all except –

A. Accidental hemorrhage

B. Black water fever

C. Amniotic fluid embolism

D. Overdosage with Vitamin K

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Answer

A. Accidental hemorrhage

B. Black water fever

C. Amniotic fluid embolism

D. Overdosage with Vitamin K

Question 3

Warm antibody hemolytic anemia is seen in all expect

A. Stibophen

B. Methyl dopa

C. Penicillin

D. Quinidine

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Answer

A. Stibophen

B. Methyl dopa

C. Penicillin

D. Quinidine

Question 4

Anticoagulant used for chelating calcium –

A. E DTA

B. Oxalate

C. Sodium citrate

D. All of the above

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Answer

B. Oxalate

C. Sodium citrate

D. All of the above

Question 5

Patient with cirrhosis is positive HBs Ag+ and has increased levels of alpha feto protein. What is the most probable diagnosis ?

A. Submassive hepatic necrosis

B. Hepatocellular carcinoma

C. Massive hepatic necrosis

D. None of the above

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Answer

A. Submassive hepatic necrosis

B. Hepatocellular carcinoma

C. Massive hepatic necrosis

D. None of the above

Question 6

Both antibody-dependent and independent complement pathway converge on which complement component?

A. C5

B. C3

C. Clq

D. C8

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Answer

A. It regulates cetain genes involved in cell cycle regulation

B. Its increased levels can induce apoptosis

C. Its activity in the cells decreases following UV irradiation and stimulates cell cycle

D. Mutations of the p53 gene are the most common genetic alteration seen in human cancer

Answer

C. B-catenin

D. Mismatch repair

Answer

A. Ionising radiation

B. Myelofibrosis

C. Infectious mononucleosis

D. Polycythemia vera

Question 7

The following statements are true about Tumour Suppressor Gene p53 except –

A. It regulates cetain genes involved in cell cycle regulation

B. Its increased levels can induce apoptosis

C. Its activity in the cells decreases following UV irradiation and stimulates cell cycle

D. Mutations of the p53 gene are the most common genetic alteration seen in human cancer

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Question 8

“Colon Carcinogenesis” is associated with all except:

A. APC

B. k RAS

C. B-catenin

D. Mismatch repair

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Question 9

Conditions predisposing to leukemia include all except –

A. Ionising radiation

B. Myelofibrosis

C. Infectious mononucleosis

D. Polycythemia vera

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Question 10

Most commonly affected organ in the disorder characterized by the peripheral blood smear is:

A. Lungs

B. Kidney

C. Spleen

D. Liver

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Mcq Subject: Pathology

A 60-year-old farmer presents with multiple patches of discoloration on his face. Biopsy of lesional skin reveals actinic keratosis. Which of the following terms best describes this response of the skin to chronic sunlight exposure?

DIC is seen with all except –

Warm antibody hemolytic anemia is seen in all expect

Anticoagulant used for chelating calcium –

Patient with cirrhosis is positive HBs Ag+ and has increased levels of alpha feto protein. What is the most probable diagnosis ?

Both antibody-dependent and independent complement pathway converge on which complement component?

The following statements are true about Tumour Suppressor Gene p53 except –

“Colon Carcinogenesis” is associated with all except:

Conditions predisposing to leukemia include all except –

Most commonly affected organ in the disorder characterized by the peripheral blood smear is:

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