Mcq Subject: Pathology

A healthy 30-year-old woman comes to the physician for a routine health maintenance examination. No abnormalities are found on physical examination. A screening Pap smear shows cells consistent with a low-grade squamous intraepithelial lesion (LSIL). Subsequent cervical biopsy specimens confirm the presence of cervical intraepithelial neoplasia (CIN) I. Which of the following risk factors is most likely related to her Pap smear findings?

A. Diethylstilbestrol (DES) exposure

B. Multiple sexual partners

C. Oral contraceptive use

D. Prior treatment for a malignancy

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Tumorgenesis in Aging is due to:

A. Telomerase reactivation

B. Telomerase inactivation

C. Increased apoptosis

D. Suppression of proto-oncogenes

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True about apoptosis is all, except –

A. Considerable apoptosis may occur in tissues before it becomes apparent in histology

B. Apoptotic cells appear round mass of the intensely eosinophillic cytoplasm with dense nuclear chromatin fragments

C. Apoptosis of cells induce inflammatory reaction

D. Macrophages phagocytose the apoptotic cells and degrade them.

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Centromere is almost at the tip of the chromosome in:

A. Metacentric

B. Submetacentric

C. Acrocentric

D. Telocentric

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“Stary sky” appearance is seen in –

A. Burkitt's lymphoma

B. Mantle cell lymphoma

C. Extra nodal marginal Zone B-cell lymphoma of MALT type

D. Chronic myeloid leukemia

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Which statement is false regarding familial adenomatous polyposis :

A. Males are usually carriers

B. Autosomal dominant inheritance

C. If not treated progress to malignancy in 100% of cases

D. Males and females are affected equally.

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The organ most vulnerable to ischaemia due to shock-

A. Lungs

B. Adrenals

C. Kidney

D. Heart

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The amount of potassium delivered to this patient after giving one bottle?

A. 2 mmol

B. 4 mmol

C. 8 mmol

D. 10 mmol

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Fordyce granules mostly occurs in all of the following areas EXCEPT

A. Vermillion of the lip

B. Posterior tonsillar pillar

C. Alveolar ridge

D. Palate

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A 50-year-old male presented with left upper quadrant pain. On examination, the spleen was palpable 10 cm below left costal margin. Peripheral smear is shown below. Which of the following IHC is used for diagnosis of the condition?

A. CD23

B. CD21

C. Annexin A1

D. Cyclin D1

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