Mcq Subject: Pathology
An 11-year-old girl becomes infected with hepatitis A and experiences mild nausea for 1 week. On physical examination, she has minimal right upper quadrant tenderness and scleral icterus. Laboratory findings include a serum AST of 68 U/L, ALT of 75 U/L, and total bilirubin of 5.1 mg/dL. Her laboratory findings most likely result from which of the following changes in her hepatocytes?
A. Cell membrane defects
B. Lysosomal autophagy
C. Mitochondrial swelling
D. Nuclear chromatin clumping
View DescriptionFrozen section examination demonstrates fibrosis and cystic spaces. Also seen are areas of compressed glands with a lobular orientation. The glands are lined by a single layer of epithelial cells with oval nuclei and regular arrangement. No true invasion of glands into the adjacent stroma is seen. This patient probably has which of the following?
A. Atypical ductal hyperplasia
B. Ductal carcinoma in situ
C. Lobular carcinoma in situ
D. Sclerosing adenosis
View DescriptionAll of the following condition(s) are associated with raised ANCA, except –
A. Wegener's granulomatosis
B. Polyarteritis Nodosa
C. Microscopic Polyangitis
D. Churg-Strauss syndrome
View DescriptionMalignant gastric ulcers are characterized by A/E ?
A. Malignant gastric ulcers are characterized by A/E ?
B. Mucosal rugae stop far of ulcers
C. Eccentric crater
D. Margins are raised
View DescriptionThe alveoli are filled with exudate the air is displaced conveing the lung into a solid organ. This description suggests-
A. Chronic bronchitis
B. Bronchial asthma
C. Bronchiectasis
D. Lobar pneumonia
View DescriptionCommon complement component for both the pathways is the following:
A. C3
B. C5
C. Clq
D. C8
View DescriptionAssessment and aiding for development of funds for the National Blindness Control Programme is done by
A. WHO
B. UNICEF
C. DANIDA
D. World Bank
View DescriptionHepatic fibrosis is associated with which of the following
A. Medullary cystic kidney
B. ADPKD
C. ARPKD
D. Nephronopthosis
View DescriptionAll is true about Giant cell arteritis except –
A. Most commonly involved artery is abdominal aorta
B. Involves large to small sized arteries
C. Granulomatous inflammation
D. Segmental nature of the involvement
View DescriptionA 36-year-old woman has become increasingly icteric for 1 month. She has had several bouts of colicky, midabdominal pain for 3 years. On physical examination, she has generalized jaundice with scleral icterus. Her BMI is 32. There is tenderness in the right upper quadrant, and the liver span is normal. A liver biopsy is obtained, and microscopic examination shows bile duct proliferation and intracanalicular bile stasis, but no inflammation or hepatocyte necrosis. The level of which of the following is most likely to be increased in the patient’s serum?
A. Alkaline phosphatase
B. Ammonia
C. Antimitochondrial antibody
D. Hepatitis C antibody
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