Mcq Subject: Pathology

Antinuclear antibody specific for SLE is

A. Anti ds DNA

B. Anti nuclear antibodies

C. Anti centromere antibody

D. Anti histone Ab

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All are true in megaloblastic anaemia except –

A. Microcytes

B. Megakaryocytes

C. Decrease in Platelets

D. Neurological symptoms

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A 2-year-old boy is brought in by his mother because of the bloody stool after ingestion of unknown amount of rat poison (coumarin based). He is admitted and treated with fresh frozen plasma and vitamin K after his prothrombin time (PT) was found to be prolonged. What is the reason for bloody stool in this case?

A. Local irritation of bowels because of the ingestion of rodenticide

B. Coumarin is antagonizing vitamin K reductase necessary for production of factors VIII and IX

C. Coumarin is antagonizing vitamin K reductase necessary for production of factors II, VII, IX & X

D. Coumarin caused disseminated intravascular coagulation (DIC)

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Linitis plastica is seen in

A. Carcinoma of liver

B. Carcinoma stomach

C. Carcinoma lung

D. Carcinoma esophagus

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Intracellular accumulation of which of the following forms Russell bodies ?

A. Immunoglobulins

B. Cholesterol

C. Phospholipids

D. Lipoproteins

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Which of the following presents with microcytic, hypochromic anemia: March 2013 (b, c)

A. Megaloblastic anemia

B. Iron deficiency anemia

C. Aplastic anemia

D. All of the above

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If a mother is donating her kidney to son, this is an example of which of the following?

A. Isograft

B. Allograft

C. Autograft

D. Xenograft

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Which of these does not cause crescentic glomerulo nephritis –

A. Rapidly progressive glomerulonephritis

B. Alpo syndrome

C. Goodpasture syndrome

D. Henoch schonlein purpura

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CD – 95 in apoptosis; the death receptors initiated through –

A. Induces apoptosis when it engaged by fas ligand system

B. Cytochrom C binds to a protein Apoptosis activating (Apaf -1) factor - 1

C. Apoptosis may be initiated by caspase activation

D. Apoptosis mediated through DNA damage

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Which of the following is usually bilateral carcinoma of breast?

A. Paget's disease

B. Ductal carcinoma

C. Lobular carcinoma

D. Medullary carcinoma

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