Mcq Subject: Pathology

Finnish of nephrotic syndrome is caused by defect in following protein aEUR’

A. Nephrin

B. Podocin

C. Alpha actinin

D. CD2 activated protein

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A 27-year-old, previously healthy man suddenly collapses at a party where both legal and illicit drugs are being used. En route to the hospital, he requires resuscitation with defibrillation to establish a normal cardiac rhythm. On physical examination, his temperature is 40deg C; respirations, 30/ min; heart rate, 110/min; and blood pressure, 175/90 mm Hg. He has dilated pupils, a perforated nasal septum, and a prominent callus on the right thumb. CT scan of the head shows an acute right frontal lobe hemorrhage. Which of the following substances is most likely responsible for these findings?

A. Amphetamine

B. Barbiturate

C. Cocaine

D. Ethanol

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Which of the following is not a tumor marker –

A. CEA

B. Tyrosinase

C. Human leucocyte antigen A2

D. AFP

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A 42-year-old man experiences malaise and increasing icterus for 2 weeks. Physical examination shows jaundice, but there are no other significant findings. Serologic test results are positive for IgM anti-HAV and negative for anti-HCV, HBsAg, and IgM anti-HBc. Which of the following outcomes is most likely to occur in this man?

A. Chronic active hepatitis

B. Complete recovery

C. Fulminant hepatitis

D. Hepatocellular carcinoma

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a1 antitrypsin deficiency is seen in

A. Bronchial asthma

B. Emphysema

C. Bronchiectasis

D. Lung carcinoma

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Diagnostic feature of parathyroid carcinoma is ?

A. Cytology

B. Metastasis

C. Clinical features

D. All

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Delayed prolonged increase in vascular permeability in inflammation is due to:

A. Interleukin 1 mediated endothelial retraction

B. Increased transcytosis

C. Leakage from newly formed blood vessels

D. Release of histamine causing endothelial contraction

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Calcification of soft tissues without any distrubance of calcium metabolism is called:

A. Ionotrophic calcification

B. Monotrophic calcification

C. Dystrophic calcification

D. Calcium induced calcification

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Bile infarct is related to –

A. Hepatitis B

B. Dubin Johnson syndrome

C. Extrahepatic cholestasis

D. Intraphepatic cholestasis

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Neurological symptoms and premature graying of hair is associated with:

A. Folic acid deficiency

B. Pernicious anaemia

C. Plummer-Vinson syndrome

D. Paterson-Kelly syndrome

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