Mcq Subject: Pathology

Which of the following is a finding in biopsy of mesothelioma of pleura-

A. Myelin figurers

B. Desmosomes

C. Wiebel-Palade bodies

D. Intense fibrosis

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Glomerulonephritis associated with AIDS is?

A. Focal segmental GN

B. PSGM

C. MPGN

D. Membranous GN

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Which of the following is not a component of Jones criteria for diagnosing acute rheumatic fever: March 2008

A. Pancarditis

B. Migratory polyahritis

C. Erythema nodosum

D. Sydenham chorea

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Biopsy of a persistent exophytic area on the vulva of a 60 year old woman demonstrates a squamous epithelial lesion. No koilocytes are seen. The lesions show papillary projections composed of disordered, squamous epithelium with well differentiated cells. The basement membrane at the dermal-epidermal junction is focally disrupted by squamous cell groups extending deep into the dermis. Which of the following diagnoses is most accurate?

A. Condyloma acuminatum

B. Extramammary Paget's disease

C. Vulvar intraepithelial neoplasia

D. Vulvar squamous cell carcinoma

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An 86-year-old man has become progressively unable to live independently for the past 10 years, and he now requires assistance with bathing, dressing, toileting, feeding, and transfers in and out of chairs and bed. On physical examination, he has no motor or sensory deficits. He cannot give the current date or state where he is. Six months later, he suddenly becomes comatose and dies. At autopsy, there is a large superficial left parietal lobe hemorrhage. Histologic examination of the brain shows numerous neocortical neuritic plaques and neurofibrillary tangles. The peripheral cerebral arteries and the core of each plaque stain positively with Congo red. Which of the following mechanisms is most likely responsible for his disease?

A. Aggregation of Ab peptide

B. Conformational change in the prion protein (PrP)

C. Dopamine deficiency

D. Expansion of polyglutamine repeats

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White piedra is caused by

A. Piedraia hoae

B. Pityrosporum orbiculares

C. Hoae werneckii

D. Trichosporon beigelii

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Mutations in Marfans syndrome is in:

A. Collagen

B. Fibrillin

C. Elastin

D. Fibrin

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True Statement about silicosis –

A. Produces pleural plaque

B. Associated with tuberculosis

C. Lower lobe infiltration

D. All

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What does cardiac polyp means –

A. Acute infarct

B. Cardiac aneurysm

C. Benign tumour

D. Fibrinous clot

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Microangiopathic hemolytic anaemia (MAHA) is a component of all of the following, except:

A. Thrombotic thrombocytopenic purpura (TTP)

B. Hemolytic uremic syndrome (HUS)

C. Hemolysis with elevated liver enzymes and low platelet (HELLP) syndrome

D. Paroxysmal nocturnal hemoglobinuria

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