Mcq Subject: Pathology

Enzyme-deficient in Alkaptonuria

A. Phenylalanine hydroxylase

B. Cystathionine synthase

C. Homogentisic acid oxidase

D. Tyrosinase

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Trophic ulcers are caused by all of the following except: September 2007

A. Syringomyelia

B. Varicose veins

C. Leprosy

D. Prolonged recumbency

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Irreversible cell injury is indicated by –

A. Accumulation of calcium in mitochondria

B. Myelin figures

C. ATP depletion

D. Shifting of ribosomes

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The most common malignant neoplasm of infancy is –

A. Malignant teratoma

B. Neuroblastoma

C. Wilms' tumor

D. Hepatoblastoma

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All are autosomal recessive coagulopathies except

A. Bernad soulier syndrome

B. Glanzmann Thrombasthenia

C. Afibrinogenemia

D. Von Willebrand disease

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Deficiency of E-cadherin is seen in?

A. Intestinal carcinoma

B. Thyroid carcinoma

C. Colon cancer

D. Gastric cancer

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Most common cause of Cervical neoplasia is?

A. HPV-6

B. HPV-11

C. HPV-16

D. HHV

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Pyroptosis is associated with which of the following cytokines?

A. IL-1

B. IL-2

C. IL-5

D. IL-6

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A 45-year-old man presents to his physician with hematuria. Renal biopsy demonstrates a focal necrotizing glomerulitis with crescent formation. The patient has a history of intermittent hemoptysis and intermittent chest pain of moderate intensity. A previous chest x-ray had demonstrated multiple opacities, some of which were cavitated. The patient also has chronic cold-like nasal symptoms. Which of the following is the most likely diagnosis?

A. Aspergillosis

B. Polyaeritis nodosa

C. Renal carcinoma metastatic to the lung

D. Wegener's granulomatosis

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This gene mapping indicates:

A. Klinefelter syndrome

B. Cri du chat syndrome

C. Eagle’s syndrome

D. Down’s syndrome

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