Mcq Subject: Pathology

Which of the following is not a tumor marker:

A. CEA

B. Tyrosinase

C. Human leucocyte antigen A2

D. AFP

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A 3-year-old child’s mother notes that a large port wine stain on the left side of the child’s face has not diminished in size since birth. This irregular, slightly raised, red-blue area is not painful, but is very disfiguring. Histologically, this lesion is most likely composed of a proliferation of which of the following tissue components?

A. Capillaries

B. Fibroblasts

C. Lymphatics

D. Lymphoblasts

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Which of the following is true about alpha 1 antitrypsin?

A. Inhibits elastase

B. Inhibits trypsinogen activation in pancreas

C. Inhibits trypsin activating protease

D. Inhibits chymotrypsin

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The most common indication for liver transplantation in end stage liver disease is

A. Wilson's disease

B. Chronic hepatitis B

C. Chronic hepatitis C

D. Alcoholic liver injury

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Increased IgA deposits are seen in –

A. Henoch Schonlein Purpura

B. Minimal Change Glomerulonephritis

C. Chronic Pyelonephritis

D. Haemolytic Uraemic Syndrome

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No change of genetic material occurs in which of the following cytogenetic abnormalities?

A. Deletion

B. Inseion

C. Translocation

D. Inversion

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What is the mechanism of acute rheumatic fever –

A. Cross reactivity with endogenous antigen

B. Innocent by slender effect

C. Due to toxin secretion by streptococci

D. Release of pyrogenic cytokines

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Tumor-containing cells of all three germ layers are called –

A. Leiomyoma

B. Squamous cell carcinoma

C. Adenocarcinoma

D. Teratoma

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In a 70 year old male who was working in asbestos factory for 10-15 years. On routine X-ray, a mass was seen in right apical region of the lung. Biopsy was taken from the mass, Which of the following is seen on electron microscopic examination –

A. Neumerous long, slender microvilli

B. Melanosomes

C. Desmosomes

D. Neurosecretary granules in the cytoplasm

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Which of the following is seen in hyperemia?

A. Decreased arteriolar blood flow to the tissue

B. Increased arteriolar blood flow to the tissue

C. Increased venous blood flow in the tissue

D. Decrease venous blood flow in the tissue

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