Mcq Subject: Pathology
Which of the following are apoptosis assays?
A. Annexin V assay
B. TUNEL technique
C. Transglutaminase activity
D. All of the above
View DescriptionA 6-year-old girl has become increasingly lethargic over the past 2 weeks. On examination, she has puffiness around the eyes. Her temperature is 36.9degC, and her blood pressure is 100/60 mm Hg. Laboratory findings show serum creatinine, 0.7 mg/ dL; urea nitrogen, 12 mg/dL; and cholesterol, 217 mg/dL. Urinalysis shows pH, 6.5; specific gravity, 1.011; 4+ proteinuria; lipiduria; and no blood or glucose. The 24-hour urine protein level is 3.8 g. The child’s condition improves after glucocorticoid therapy. Which of the following findings by electron microscopy is most likely to characterize this disease process?
A. Areas of thickened and thinned basement membrane
B. Effacement of podocyte foot processes
C. Increased mesangial matrix
D. Reduplication of glomerular basement membrane
View DescriptionPathognomic finding of rabies is: March 2012
A. Obliterative endaeritis
B. Microglial nodules
C. Neuronophagia
D. Negri bodies
View DescriptionThe tumor suppressor gene P53 induces cell arrest at-
A. G2 - M phase
B. S G2 phase
C. G1 - S phase
D. Go - phase
View DescriptionFor the past week, a 65-year-old woman has been treated for a severe infection with broad-spectrum antibiotics, and she had recovered well. Over the past day, however, she has developed foul-smelling, voluminous, greenish, watery diarrhea, as well as abdominal pain and fever. She is diagnosed with pseudomembranous colitis. Which of the following is the mechanism associated with this condition?
A. Aggregation of bacterial colonies on the lumen, forming pseudomembranes
B. Bacterial release of exotoxin, inducing necrosis of the mucosa
C. Physical invasion of bacteria into the superficial mucosa, leading to pseudomembrane formation
D. Selective killing of C. difficile bacteria by antibiotics
View DescriptionKoener’s tumor are seen in?
A. Tuberous sclerosis
B. Neurofibromatosis
C. VHL
D. NF
View DescriptionWhich of the following is not a feature of sickle cell disease?
A. Autosplenectomy
B. Heterozygous individuals are at increased risk of Plasmodium falciparum infection
C. Ischemic tissue damage
D. Hydroxyurea is used as a therapeutic agent
View DescriptionAll are a complication of Typhoid ulcer, EXCEPT –
A. Perforation
B. Stricture
C. Haemorrhage
D. Sepsis
View DescriptionSudden death, right sided heart failure (cor pulmonate or cardiovascular collapse occur when
A. Small pulmonary embolism
B. Massive pulmonary embolism
C. 60% or more of pulmonary artery is obstructed with emboli
D. End artery obliteration
View DescriptionAll of the following statement are true regarding esophageal atresia, except:
A. There is absence of esophagus
B. It is a mechanical obstruction
C. It occurs most commonly at or near the tracheal bifurcation
D. It is associated with other congenital anomalies
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