Mcq Subject: Pathology

The histology of Lobular carcinoma of breast reveals-

A. Single file pattern

B. Pleomorphic cells in sheets

C. Clustersl/lslands of cells with mucous lakes

D. Solid syncytium like sheets

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Extragonadal germ cell tumors occur in all of the following except –

A. Sacrococcygeal region

B. Mediastinum

C. Brain

D. Testis

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Reilly bodies are inclusion bodies seen in hurler’s disease within

A. Lymphocytes

B. Fibroblast

C. RBC

D. WBC

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Comment on the diagnosis?

A. Down syndrome

B. Turner syndrome

C. Prader-Willi syndrome

D. Patau syndrome

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Foam cells are formed by?

A. Neutrophills

B. Fibroblasts

C. Macrophages

D. All of them

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The most characteristic histological finding of acute rheumatic carditis is –

A. Fibrinous pericarditis

B. Vegetations on mitral valve leaflets

C. Aschoff bodies in myocardium

D. Increased vascularity of the valves

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A 50-year-old woman is discovered to have metastatic breast cancer. One week after receiving her first dose of chemotherapy, she develops bacterial pneumonia. Which of the following best explains this patient’s susceptibility to bacterial infection?

A. Depletion of serum complement

B. Impaired neutrophil respiratory burst

C. Inhibition of clotting factor activation

D. Neutropenia

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Platelets are stored at

A. 5°C for 1 month

B. 20-24°C for 5 days

C. -4°C for 3 months

D. 20-24°C for 3 days

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In Huntington chorea the causative mutation in the protein huntingtin is a:

A. Point mutation

B. Gene deletion

C. Frameshift mutation

D. Trinucleotide repeat expansion

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Chediak Higashi syndrome is characterized by?

A. Giant granules in leukocytes

B. Albinism

C. Mutation in LYST gene

D. All the above

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