Mcq Subject: Pathology

Gene for major histocompatibility complex is located on which chromosome?

A. Chromosome 10

B. Chromosome 6

C. X chromosome

D. Chromosome 13

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Eosinophilic abscess in lymph node is characteristically seen in –

A. Kimura's disease

B. Hodgkin's lymphoma

C. Tuberculosis

D. Sarcoidosis

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Which of the following would distinguish hydrocephalusdue to aqueductal stenosis when compared to thatdue to Dandy walker malformation:

A. Third ventricle size

B. Posterior fossa volume.

C. Lateral ventricular size

D. Head circumference.

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A 33-year-old woman discovers a lump in her left breast on self-examination. Her mother and sister both had breast cancer. A mammogram demonstrates an ill-defined density in the outer quadrant of the left breast, with microcalcifications. Needle aspiration reveals the presence of malignant, ductal epithelial cells. Genetic screening identifies a mutation in BRCA1. In addition to cell cycle control, BRCA1 protein promotes which of the following cellular functions?

A. Apoptosis

B. Cell Adhesion

C. DNA Repair

D. Gene Transcription

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A study of persons receiving emergent medical services is conducted. It is observed that 5% of persons with sudden cardiac arrest who receive cardiopulmonary resuscitation survive. Which of the following is the most likely mechanism for cardiac arrest in these survivors?

A. Arrhythmia

B. Infarction

C. Inflammation

D. Valve failure

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Cyst which develops from Rests of Serres is:

A. Residual cyst

B. Odontogenic keratocyst

C. Dentigerous cyst

D. Radicular cyst

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Increased permeability in acute inflammation is due to –

A. Histamine

B. IL-2

C. TGF-b

D. FGF

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A 40 years old male had undergone splenectomy 20 years ago. Peripheral blood smear examination would show the presence of:

A. Dohle bodies

B. Hypersegmented neutrophils

C. Spherocytes

D. Howell-Jolly bodies

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DAX 1 gene Mutation is associated with

A. Cushing's disease

B. Hashimoto's disease

C. Congenital adrenal hypoplaisa

D. Addison's disease

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Which of the following is not a cachetic gene?

A. APEH

B. MC4R

C. Smad7

D. Smad3

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