Mcq Subject: Pathology

A 35-year-old man has a 5-year history of episodic wheezing and coughing. The episodes are more common during the winter months, and he has noticed that they often follow minor respiratory tract infections. In the period between the episodes, he can breathe normally. There is no family history of asthma or other allergies. On physical examination, there are no remarkable findings. A chest radiograph shows no abnormalities. A serum IgE level and WBC count are normal. Which of the following is the most likely mechanism that contributes to the findings in his illness?

A. Accumulation of alveolar neutrophilic exudate

B. Bronchial hyperreactivity to chronic inflammation

C. Emigration of eosinophils into bronchi

D. Hyperresponsiveness to Aspergillus spores

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The skin pigmentation in bronze diabetes is due to-

A. Hemosiderin

B. Lipofuscin

C. Melanin

D. Both melanin & hemosiderin

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Bloody pericardial effusion can be due to ?

A. Uremic pericarditis

B. Tuberculosis pericarditis

C. Tumour infiltration

D. All of the above

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MOST common mutation seen in heriditary hemochromatosis is:

A. C282Y

B. H63D

C. TFR2

D. SLC11A3

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What is the percentage of immunoglobulins present in proteins

A. 5-10%

B. 10-15%

C. 15-20%

D. 20-25%

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Which of the following statements about carcinogenesis is false?

A. Asbestos exposure increases the incidence of lung cancer

B. Papilloma viruses produce tumors in animals but not in humans

C. Exposure to aniline dyes predisposes to cancer of the urinary bladder

D. Hepatitis B virus has been implicated in hepatocellular carcinoma

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Which of the following enzyme degrades brain natriuretic peptide?

A. Neutral endopeptidase

B. Elastase

C. Collagenase

D. Omapatrilat

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A Syndrome is characterized by Pancreaticneoplasm (insulinoma), Pituitary, and Parathyroid involvement. The syndrome is:

A. Polyglandular Type I

B. Polyglangular Type 2

C. Wermer

D. Sipple

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AH of the following are true about lymphocyte depletion variety of HL except:

A. Least common

B. CD 20 expression

C. CD 15 & CD 30 expression

D. Pleomorphic RS cell

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Commonest cause of Intra cerebral bleed –

A. Berry aneurysms

B. Hypeension

C. Diabetes

D. Thrombocytopenia

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