Mcq Subject: Pathology

All of the following statements regarding adult polycystic kidney disease are TRUE, EXCEPT:

A. Autosomal dominant inheritance

B. Hypeension is rare

C. Can be associated with cysts in liver, lungs and pancreas

D. Pyelonephritis is common

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Misfolding of proteins is associated with the following except

A. Alzheimer's disease

B. Bovine spongiform encephalopathy

C. Tuberculosis

D. Cystic fibrosis

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Touton giant cells are found in:

A. Xanthomas

B. Dermatofibromas

C. Actinic keratosis

D. Benign nevocellular nevus

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Stem cells are?

A. Labile

B. Stable

C. Permanent

D. None

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A patient presents with mediastinal mass with sheets of epithelial cells giving arborizing pattern of reactivity alongwith interspersed lympoid cells. The apt diagnosis would be –

A. Thymoma

B. Thymic carcinoid

C. Primary mediastinal lymphoma

D. Non-Hodgkin lymphoma

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A 14-year-old boy complains of a 4-month history of fatigue, abdominal pain, and yellowing of his eyes and skin. Physical examination shows tremor of both hands, lack of coordination, and mild jaundice. An ophthalmic examination reveals Kayser-Fleischer rings. Degenerative changes are present in which of the following anatomic regions of the CNS in this patient?

A. Cerebellum

B. Corpus striatum

C. Paraventricular white matter

D. Pons

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A 56-year-old diabetic woman has recently been treated with a 2-week course of antibiotics for a skin infection. She returns to the clinic for follow-up with a new complaint of a “cottage cheese-like” vaginal discharge with significant vaginal itching. The most likely cause of these symptoms is

A. C. granulomatis.

B. C. albicans.

C. Chancroid.

D. Neisseria meningitidis.

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All are predisposing factors of Deep Vein thrombosis, except

A. Cushing's syndrome

B. Hip surgery

C. Lower limb trauma

D. Subungual melanoma

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Tophus is the pathognomic lesion of which of the following condition –

A. Multiple myeloma

B. Cystinosis

C. Gout

D. Eale's disease

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Which of the following is the most common mutation in Ewing’s sarcoma –

A. Translocation X : 18

B. Translocation 11; 22

C. Activative mutation of G5alpha surface protein

D. Missense mutation in EXTI

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