Mcq Subject: Pathology

A 25-year-old woman has a 3-year history of arthralgias. Physical examination shows no joint deformity, but she appears pale. Laboratory studies show a total RBC count of 4.7 million/ mm3, hemoglobin of 12.5 g/dL, hematocrit of 37.1%, platelet count of 217,000/ mm3, and WBC count of 5890/ mm3. The peripheral blood smear shows hypochromic and microcytic RBCs. Total serum iron and ferritin levels are normal. Hemoglobin electrophoresis shows 93% hemoglobin A1 with elevated hemoglobin A2 level of 5.8% and hemoglobin F level of 1.2%. What is the most likely diagnosis?

A. Anemia of chronic disease

B. Autoimmune hemolytic anemia

C. b-Thalassemia minor

D. Infection with Plasmodium vivax

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Subepithelial deposits in kidney are seen in-

A. MPGN-1

B. GPS

C. PSGN

D. All

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Vasodilation in acute inflammation is first shown by

A. Venules

B. Arterioles

C. Capillaries

D. Vein

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Chubby cheeks, eyes are blue and staring at the sky is a feature of

A. Cherubism

B. Fibrous dysplasia

C. Ectodermal dysplasia

D. Sicca syndrome

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A 25-year-old man with a history of autism and mental retardation is seen by a genetic counselor. The man has coarse facial features, an increased head circumference, and macro-orchidism. His maternal uncle is similarly affected. After further evaluation, a diagnosis of fragile X syndrome is rendered. What is the most likely underlying cause of this patient’s genetic disease?

A. Chromosomal nondisjunction

B. Chromosome inversion

C. Expansion of trinucleotide repeat

D. Frame-shift mutation

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Pernicious anemia associated with ?

A. Gastric pathology

B. Renal pathology

C. Esophageal pathology

D. Oral pathology

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Inherited cancer syndrome include all except?

A. Retinoblastom

B. Neurofibroma

C. Xeroderma pigmentosa

D. Familial polyposis coli

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All are components of basement membrane except –

A. Nidogen

B. Laminin

C. Entactin

D. Rhodopsin

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All are true about Giant cell arteritis except –

A. Involves large to small sized arteries

B. Granulomatous inflammation

C. Most commonly involved artery is abdominal aorta

D. Segmental nature of the involvement

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Lung granuloma with necrosis are seen in -a) PANb) TBc) Histoplasmosisd) Cryptococcosise) Wegener’s granulomatosis

A. bce

B. bc

C. acd

D. ace

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