Mcq Subject: Pathology

A 25-year-old woman sustains a deep, open laceration over her right forearm in a motorcycle accident. The wound is cleaned and sutured. During the next 3 months, the wound heals with formation of a linear scar. Which of the following nutritional factors is required for proper collagen assembly in the scar tissue of the patient?

A. Folic acid

B. Thiamine

C. Vitamin A

D. Vitamin C

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Lipid in tissue detected by –

A. Oil Red O

B. Muciramine

C. PAS

D. Myeloperoxidase

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Streptococcal cross reactivity affects which organ?

A. Heart

B. Skin

C. Joint

D. All of the above

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A 45-year-old woman presents with a 6-month history of fatigue and swelling in her neck. Physical examination shows a goiter. A CBC discloses megaloblastic anemia and a normal reticulocyte count. Additionally, there is an elevated serum level of TSH and antithyroid antibodies. Needle aspiration of the left lobe of the thyroid reveals benign follicular cells and numerous lymphocytes. Anemia in this patient is most likely caused by antibodies directed to which of the following targets?

A. Chief cells

B. Intrinsic factor

C. Paneth cells

D. TSH receptor

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In Wintrobe’s method for ESR, anticoagulant used is -a) Double oxalate b) EDTAc) Trisodium citrated) Citrate

A. ac

B. a

C. ab

D. bc

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A 20 year old man has a testicular mass, which on orchiectomy shows a malignant tumor with yolk sac differentiation. Which of the following tumor markers would probably be most useful in monitoring the patient for recurrent or metastatic disease?

A. Alpha-fetoprotein

B. Bombesin

C. Carcinoembryonic antigen (CEA)

D. Prostate-specific antigen (PSA)

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A 55-year-old woman following major abdominal surgery has had discomfort and swelling of her left leg for the past week. On physical examination, the leg is slightly difficult to move, and on palpation there is tenderness. A Doppler sonogram shows thrombosis of deep left leg veins. Which of the following mechanisms is most likely to contribute to her condition?

A. Hypercalcemia

B. Immobilization

C. Ingestion of aspirin

D. Nitric oxide release

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Histology of Alpo syndrome –

A. Foamy cells in interstitium

B. Foamy cells in tubular epithelial cells

C. Thickening of GBM > 100 nm

D. All

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Which of the following pathogenic mechanism is involved in the generation of sarcoidosis:

A. Intra-alveolar and interstitial accumulation of CD4+ T cells

B. Increased levels of T cell-derived TH1 cytokines such as IL-2 and IFN-g

C. Increased levels of cytokines in the local environment IL-8, TNF

D. All of the above

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A married middle aged female gives history of repeated aboions for the past 5 years. The prenatal karyogram of the conceptus is given below: This karyogram suggests the following:

A. Klinefelter's syndrome

B. Turner's syndrome

C. Down's syndrome

D. Patau's syndrome

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