Mcq Subject: Pathology

A patient presented with a platelet count of 700 x 109/L with abnormalities in size, shape and granularity of platelets. WBC count of 8 x109 L, hemoglobin of 12 g/dl and the absence of the Philadelphia chromosome. The most likely diagnosis would be?

A. Polycythemia vera

B. Essential thrombocythemia

C. Chronic myeloid leukemia

D. Leukemoid reaction

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Mallory bodies are seen in?

A. Hepatitis B infection

B. Hydatid cyst

C. al - antitrypsin deficiency

D. Autoimmune hepatitis

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Best site for taking biopsy for viral oesophagitis is-

A. Edge of ulcer

B. Base of ulcer

C. Adjacent indurated area around ulcer

D. Surrounding normal mucosa

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Mutation of which of the following gene is most impoant in Paroxysmal Nocturnal Hemoglobinuria

A. Decay accelerating factor (DAF)

B. Membrane inhibitor of reactive lysis (MIRL)

C. Glycosyl phosphatidyl inositol (GPI)

D. CD8 binding protein

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Cyclo-oxygenase pathway of arachidonic acid metabolism does not give rise to:

A. Thromboxane A2

B. Prostaglandin

C. Leukotrienes

D. Prostacyclin

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Multiple myeloma on radionuclide scanning presents as

A. Cold nodule

B. Hot nodule

C. Diffuse increased uptake

D. Diffuse decreased uptake

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Gingival biopsy is useful in the diagnosis of-

A. Sarcoidosis

B. Amyloidosis

C. Histoplasmosis

D. Scurvy

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Which of the following cells are more abundant in chronic inflammation than in acute inflammation?

A. Plasma cells

B. Eosinophils

C. Neutrophils

D. Normoblasts

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Wilm’s tumor associated with all except

A. WAGR

B. Beckwith Weidman

C. Dennis dash

D. Digeorge syndrome

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Type II hypersensitivity is mediated by-

A. Immune complex

B. Ig G

C. Ig M

D. Complement

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