Mcq Subject: Pathology

Which of the following is/are true about autosomal dominant polycystic kidney disease except:

A. Many patients may be asymptomatic till 3rd or 4th decade

B. Pancreatic cyst

C. Associated with hypeension

D. Subarachnoid haemorrhage is most common extra renal complication

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The HLA class III region genes are important elements in

A. Transplant rejection phenomenon

B. Antigen presentation and elimination

C. Immune surveillance

D. Governing susceptibility to autoimmune diseases

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Bilateral contracted kidney occurs in all except

A. Diabetes mellitus

B. Benign nephrosclerosis

C. Chronic pyelonephritis

D. Chronic glomerular nephritis

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E cadherin gene deficiency is seen in:

A. Gastric cancer

B. Intestinal cancer

C. Thyroid cancer

D. Pancreatic cancer

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Which of the following is not seen in Ehlers-Danlos syndrome?

A. Kyphoscoliosis

B. Ahrochalasia

C. Dermatosparaxis

D. Pectus excavatum

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Morphologically diagnostic feature of cancer cells –

A. T Size

B. T Mitotic activity

C. T Cytoplasm

D. T Lysosomes

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In sickle cell anaemia defect is in which chain –

A. Alpha-chain

B. Beta-chain

C. Both the chains

D. None of these

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“Onion skin” fibrosis of bile duct is seen in-

A. Primary biliary cirrhosis

B. Primary sclerosing cholangitis

C. Extrahepatic biliary fibrosis

D. Congenital hepatic fibrosis

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An 18-year-old woman comes to the emergency room with recurrent facial edema, especially around her lips. She also has recurrent bouts of intense abdominal pain and cramps, sometimes associated with vomiting. Laboratory examination reveals decreased C4, while levels of C3, decay-accelerating factor, and IgE are within normal limits. A deficiency of which of the following substances is most likely to be associated with these findings?

A. C1 esterase inhibitor

B. Complement components C3 and C5

C. Decay-accelerating factor

D. None of the above

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Feature of microscopic polyangitis is –

A. IgG deposits in kidney

B. Bronchospasm

C. Renal involvement

D. All of the above

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