Mcq Subject: Pathology
Deficiency of the ‘intrinsic factor of Castle’ causes –
A. Megaloblastic anemia
B. Pernicious anemia
C. Cooley's anemia
D. Aplastic anemia
View DescriptionA 22-year-old primigravida notes absent fetal movement for 2 days. The fetus is delivered stillborn at 19 weeks’ gestation. The macerated fetus shows marked hydrops fetalis and a large posterior cystic hygroma of the neck. At autopsy, internal anomalies include aortic coarctation and a horseshoe kidney. Which of the following karyotypes is most likely to be present in cells obtained from this fetus?
A. 45, X
B. 47, XX, +18
C. 47, XX, +21
D. 47, XYY
View DescriptionMost common site of gastrointestinal stromal tumor (GIST) is:-
A. Small intestine
B. Colon
C. Stomach
D. Liver
View DescriptionThe blood in the vessels normally does not clot because:
A. Vitamin K antagonists are present in plasma
B. Thrombin has a positive feedback on plasminogen
C. Sodium citrate in plasma chelates calcium ions
D. Vascular endothelium is smooth and coated with glycocalyx
View DescriptionCytogenetics for synovial cell sarcoma
A. t (9,22)
B. t (11,14)
C. t (8,14)
D. t (x,18)
View DescriptionPredisposing factor for venous thrombosis ?
A. AT III deficiency
B. Protein S deficiency
C. Protein C deficiency
D. All
View DescriptionIn apoptosis, the nucleus is destroyed by
A. Endonuclease fragmentation
B. Karyolysis
C. Phagocytosis
D. Necrosis
View DescriptionTumor associated with tuberous sclerosis is/ are-
A. Renal angiomyoma
B. Subependymal giant cell astrocytoma
C. Rhabdomyoma heart
D. All the above
View DescriptionIn hemophilia, which of the following is raised:September 2007
A. BT
B. CT
C. PT
D. aPTT
View DescriptionA 25-year-old woman with a history of systemic lupus erythematosus presents with diffuse petechiae and fatigue. Physical examination demonstrates lymphadenopathy and splenomegaly Laboratory findings include normocytic anemia (hemoglobin =6.1 g/dL) and thrombocytopenia (30,000/mL). Which of the following is the most likely underlying mechanism in the development of thrombocytopenia in this patient?
A. Antibody-mediated platelet destruction
B. Clonal plasma cell circulating paraprotein
C. Decreased susceptibility to complement-mediated lysis
D. Defect in the platelet cytoskeleton
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