Mcq Subject: Pathology
A 40-year-old woman presents with a long history of vague upper abdominal pain and frequent indigestion with abdominal tenderness. Serum bilirubin is elevated (4.2 mg/dL). There is a mild increase in serum AST and ALT (62 and 57 U/L, respectively) and a moderate increase in alkaline phosphatase (325 U/L). Markers for viral hepatitis are negative. Abdominal ultrasound examination shows echogenic stone-like material within the gallbladder and thickening of the gallbladder wall. An intrahepatic mass is also visualized adjacent to the gallbladder. A cholecystectomy is performed. Histologic examination shows dense fibrosis and glandular structures in the wall of the gallbladder. What is the most likely diagnosis?
A. Carcinoma of the gallbladder
B. Hemangiosarcoma
C. Hepatic adenoma
D. Hepatocellular carcinoma
View DescriptionA 34-year-old woman presents with increasing abdominal girth of 3 months in duration. Physical examination reveals a left ovarian mass and mild ascites. The ovarian mass is removed, and the pathology report states “yolk sac carcinoma.” Which of the following provides the best serologic marker to monitor the course of disease in this patient after surgery?
A. Alkaline phosphatase
B. Alpha-fetoprotein
C. Carcinoembryonic antigen
D. Human chorionic gonadotropin
View DescriptionStem cells are taken from all except-
A. Liver
B. Bone marrow
C. Blood
D. Adipose tissue
View DescriptionPappenheimer bodies are
A. Ribosomal inclusions
B. Iron deposits
C. Denatured Hemoglobin
D. DNA remnants
View DescriptionGeographic tongue is of red colour because of
A. Infiltration of eosinophils
B. Infiltration of neutrophils
C. Both of the above
D. None of the above
View DescriptionMajor source of collagen in cirrhosis?
A. Kupfer cells
B. Ito cell (Hepatic stellate cell)
C. Hepatocyte
D. Canalicular cell
View Description2-year-old child is seen for a well-child visit in a pediatric clinic. Abdominal examination demonstrates a palpable, non-tender mass on the left side of the abdomen. The mother had no idea where the mass was present and the pediatrician did not note the presence of the mass at the child’s 18-month well-child visit. Physical examination is otherwise unremarkable. Abnormalities of which of the following chromosomes have been linked to this disease?
A. 3
B. 5
C. 11
D. 15
View Descriptionvon Willebrand factor is produced by –
A. Liver
B. Platelets
C. Endothelial cells
D. Spleen
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