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11830 Pathology

A 7-month-old boy has had multiple bouts of otitis media, sinusitis, bronchitis, oral candidiasis, and multiple viral infections. Cessation of the recurrent infections follows successful engraftment of a bone marrow transplant. The basis of the clinical improvement is

Adirect transfusion of antibodyproducing B cells.
Bdirect transfusion of donor CD4+ and CD8+ lymphocytes.
Cdonor suppression of recipient cytotoxic T cells
Dmaturation of donor lymphoid progenitor cells
Pathology
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