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11818 Pathology

A 7-year-old boy presented with generalized edema. Urine examination revealed marked albuminuria. Serum biochemical examinations showed hypoalbuminemia with hyperlipidemia. Kidney biopsy was undertaken. On light microscopic examination, the kidney appeared normal. Electron microscopic examination is most likely to reveal –

AFusion of foot processes of the glomerular epithelial cells
BRarefaction of glomerular basement membrane
CDeposition of electron dense material in the basement membrane
DThin basement membrane
Pathology
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11822 Pathology

Sections from a solid-cytic unilateral ovarian tumor in a 30-year old female show a tumor composed of diffuse sheets of small cells with doubtful nuclear grooving and scanty cytoplasm. No Call-Exner bodies are seen.The ideal immunohistochemistry panel would include

AVimentin, epithelial membrane antigen, inhibin, CD99
BDesmin, S- 100 protein, smooth muscle antigen, cytokeratin
CChromogranin, CD45, CD99, CD2O
DCD3, chromagranin, CD 45, synaptophysin
Pathology
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