Mcq Subject: Pathology

A couple, with a fimily history of beta thalassemia major in a distant relative, has come for counseling. The husband has HbA2 of 4.8% and the wife has HbA2 of 2.3%. The risk of having a child with beta thalassemia major is –

A. 50%

B. 25%

C. 5%

D. 0%

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In acute inflammation, Late-appearing sunburn is an example of

A. Delayed transient increase in permeability

B. Early transient increase in permeability

C. Delayed prolonged increase in permeability

D. Early permanent increase in permeability

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An 80-year-old man with long-standing diabetes and systemic hypeension dies of congestive hea failure. The luminal surface of the abdominal aoa shows atherosclerotic plaques. Which of the following is not a principal component of such plaques?

A. B lymphocytes

B. Macrophages

C. Calcium

D. Lipids

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t (2;8) is characteristically seen with –

A. Pre B cell lymphoma

B. Pre T cell lymphoma

C. Burkitt's lymphoma

D. Montel cell lymphoma

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The following features differentiate Rotor syndrome from Dubin Johnson’s syndrome EXCEPT

A. Liver in patients with Rotor syndrome has no increased pigmentation and appears normal

B. In Rotor syndrome, Gall bladder is usually visualized on cholecystography

C. Total urinary coproporphyin is substantially increased in Rotor syndrome

D. Fraction of coproporphyin I in urine is elevated usually more than 80% of the total in Rotor syndrome

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Alpha fetoprotein is raised in all except: September2011

A. Teratocarcinoma

B. Down syndrome

C. Embryonal cell carcinoma

D. Hepatocellular carcinoma

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In apoptosis, Apaf-1 is activated by release of which of the following substances from the mitochondria?

A. Bcl-2

B. Bax

C. Bcl - XL

D. Cytochrome C

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Which of the following indicates hemolysis?

A. Target cells

B. Schistocytes

C. Acantocytes

D. Basophilic stippling

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“Tophus” is the pathognomonic lesion of which of the following condition

A. Multiple myeloma

B. Gout

C. Cystinosis

D. Eales disease

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Prologed PT and Normal PTT may be seen in ?

A. Thrombocytopenia

B. DIC

C. Vit. K deficiency

D. None

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