Mcq Subject: Pathology

The following are inherited as autosomal recessive disorder except

A. Phenylketonuria

B. Galactosemia

C. Achondroplasia

D. Wilson's disease

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TSC1 gene plays a vital role in pathogenesis of a neurocutaneous syndrome called Tuberous sclerosis. It is located on which chromosome?

A. Chromosome 16

B. Chromosome 9

C. Chromosome 4

D. Chromosome 3

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In pemphigus, autoantibodies are directed against which of the following structures?

A. Acetylcholine receptor

B. Sarcomere

C. Epidermis

D. Thyroid follicle

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“Biphasic pattern” on histology is seen in which tumor-

A. Rhabdomyosarcoma

B. Synol cell sarcoma

C. Osteosarcoma

D. Neurofibroma

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TNF and IL1 are produced by ?

A. Neutrophils

B. Monocytes

C. Lymphocytes

D. Activated Macrophages

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What percent of giant cell tumor of bone are malignant?

A. 5-1O%

B. 15-2O%

C. 25-3O%

D. 50-60%

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Which of the following is not a seronegative spondyloahropathy –

A. Psoriatic ahritis

B. Ankylosing spondylitis

C. RA

D. Reiters ahritis

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Cause of ITP is-

A. Vasculitis

B. Antibody to vascular epithelium

C. Antibody to platelets

D. Antibody to clotting factors

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Antigen involved in post transplant rejection –

A. HLA - Antigen

B. Nuclear antigen

C. Polysaccharide

D. DHA

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Which of the following is not seen HIV involvement of CNS –

A. Perivascular giant cell

B. Vacuolar degeneration of post column

C. Microglial nodule formation

D. Inclusion bodies

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