Mcq Subject: Pathology

A 60 year old male patient complains of fever, pale skin, weakness and loss of appetite. Karyotyping findings reveal presence of Ph chromosome. This patient could suffer from any of the following except?

A. Chronic myeloid leukemia

B. Acute myeloid leukemia

C. Adult B cell-ALL

D. Chronic lymphocytic leukemia

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A 4-year-old child develops a runny nose and cough. After the cough persists for 2 weeks she exhibits paroxysms of coughing so severe she becomes cyanotic. On physical examination, her temperature is 37.4deg C. Her mouth and pharynx reveal no erythema or swelling. On auscultation of the chest, her lungs show crackles bilaterally. She has spasmodic coughing, with a series of coughs on a single breath, bringing up mucus plugs, followed by labored inspiration. The pathogenesis of her disease most likely results from disabling of which of the following?

A. Ciliary movement

B. Complement lysis

C. Immunoglobulin secretion

D. NK cell activation

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All of the following are characteristics of malignant tumours, except:

A. Loss of polarity

B. Metaplasia

C. Nuclear pleomorphism

D. Metastasis

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Mitochondrial DNA (mt- DN(A) is known for all except –

A. Maternal inheritance

B. Heteroplasmy

C. Leber hereditary optic neuropathy is the prototype

D. Nemaline myopathy results due to mutations in mt- DNA

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The pa of the Lens which undergoes a change in shape during accommodation is?

A. Anterior central pa

B. Posterior central pa

C. Anterior peripheral pa

D. Posterior peripheral pa

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Commonest histological finding in benign hypeension is

A. proliferating endaeritis

B. Necrotising aeriolitis

C. Hyaline aeriosclerosis

D. Cystic medial necrosis

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A couple, with a fimily history of beta thalassemia major in a distant relative, has come for counseling. The husband has HbA2 of 4.8% and the wife has HbA2 of 2.3%. The risk of having a child with betathalassemia major is –

A. 50%

B. 25%

C. 5%

D. 0%

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Which of the following type of amyloidosis presents with rheumatological manifestation in patients long term hemodialysis

A. ATTR

B. AI22 microglobulin

C. AA aEUR" Amyloid

D. AC aEUR" Amyloid

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Which of the following helps in cell to cell adhesion?

A. Interleukins

B. Interferons

C. E-Cadherin

D. Matrix metallo proteinase

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All the following organs likely undergo coagulative necrosis except-

A. Spleen

B. Heart

C. Kidney

D. Brain

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