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11618 Pathology

A 15-year-old male presents with hematuria. he has previous diagnoses of deafness and corneal dystrophy. Urinalysis shows 1 + proteins, no ketones, no glucose, 1+ blood, and no leukocytes. A renal biopsy reveals tubular epithelial foam cells by light microscopy. By electron microscopy, the glomerular basement membrane shows areas of attenuation, with splitting and lamination of lamina dense in other thickened areas. The most probable diagnosis is-

AAcute tubular necrosis
BBerger disease
CMembranous glomerulonephritis
DAlpo syndrome
Pathology
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11619 Pathology

A 59-year-old man experiences acute chest pain and is rushed to the emergency room. Laboratory studies and ECG demonstrate an acute myocardial infarction; however, coronary artery angiography performed 2 hours later does not show evidence of thrombosis. Which of the following mediators of inflammation causes relaxation of vascular smooth muscle cells and vasodilation of arterioles at the site of myocardial infarction in the patient?

ABradykinin
BHistamine
CLeukotrienes
DNitric oxide
Pathology
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