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10173 Pathology

An epidemiologic study of children with failure to thrive is undertaken in Guatemala. Some of these children with ages 1 to 3 years have repeated bouts of diarrhea, but do not improve with dietary supplements. Jejunal biopsies show blunted, atrophic villi with crypt elongation and chronic inflammatory infiltrates. What is the most likely factor contributing to recurrent diarrhea in these children?

AAbetalipoproteinemia
BBacterial infection
CChloride ion channel dysfunction
DDisaccharidase deficiency
Pathology
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